USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: P25705 USC-OGP 2-DE database:  P25705 P25705 General information about the entry View entry in simple text format Entry name ATPA_HUMAN Primary accession number P25705 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=ATP synthase subunit alpha, mitochondrial; Flags: Precursor;. Gene name Name=ATP5A1 Synonyms=ATP5A, ATP5AL2, ATPM Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_6-11 {PLATELET 6-11} Homo sapiens (Human)   map experimental info   PLATELET_6-11 MAP LOCATIONS: SPOT OGP-0911: pI=7.67; Mw=50288 SPOT OGP-0912: pI=7.73; Mw=50288 SPOT OGP-0913: pI=7.61; Mw=50153 Cross-references UniProtKB/Swiss-Prot P25705; ATPA_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name ATPA_HUMAN Primary accession number P25705 Secondary accession number(s) A8K092 B4DY56 K7ENP3 Q53XX6 Q8IXV2 Q96FB4 Q96HW2 Q96IR6 Q9BTV8 Sequence was last modified on  May 1, 1992 (version 1) Annotations were last modified on  March 15, 2017 (version 203) Name and origin of the protein Description RecName: Full=ATP synthase subunit alpha, mitochondrial; Flags: Precursor; Gene name Name=ATP5A1 Synonyms=ATP5A, ATP5AL2, ATPM Encoded on Name=ATP5A1; Synonyms=ATP5A, ATP5AL2, ATPM Keywords Acetylation; Alternative splicing; ATP synthesis; ATP-binding; Cell membrane; CF(1); Complete proteome; Direct protein sequencing; Disease mutation; Glycoprotein; Hydrogen ion transport; Ion transport; Membrane; Methylation; Mitochondrion; Mitochondrion inner membrane; Nucleotide-binding; Phosphoprotein; Polymorphism; Pyrrolidone carboxylic acid; Reference proteome; Transit peptide; Transport. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL X59066; CAA41789.1; -; mRNA EMBL X65460; CAA46452.1; -; mRNA EMBL D14710; BAA03531.1; -; mRNA EMBL D28126; BAA05672.1; -; Genomic_DNA EMBL BT007209; AAP35873.1; -; mRNA EMBL AK092735; BAG52604.1; -; mRNA EMBL AK289457; BAF82146.1; -; mRNA EMBL AK302272; BAG63618.1; -; mRNA EMBL AC012569; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL BC003119; AAH03119.1; -; mRNA EMBL BC007299; AAH07299.1; -; mRNA EMBL BC008028; AAH08028.2; -; mRNA EMBL BC011384; AAH11384.1; -; mRNA EMBL BC016046; AAH16046.1; -; mRNA EMBL BC019310; AAH19310.1; -; mRNA EMBL BC039135; AAH39135.2; -; mRNA EMBL BC064562; AAH64562.1; -; mRNA EMBL BC067385; AAH67385.1; -; mRNA CCDS CCDS11927.1; -. [P25705-1]; . CCDS CCDS58620.1; -. [P25705-2]; . CCDS CCDS59315.1; -. [P25705-3]; . PIR S17193; PWHUA; . RefSeq NP_001001935.1; NM_001001935.2. [P25705-2]; . RefSeq NP_001001937.1; NM_001001937.1. [P25705-1]; . RefSeq NP_001244263.1; NM_001257334.1. [P25705-3]; . RefSeq NP_001244264.1; NM_001257335.1. [P25705-2]; . RefSeq NP_004037.1; NM_004046.5. [P25705-1]; . UniGene Hs.298280; -; . ProteinModelPortal P25705; -; . SMR P25705; -; . BioGrid 106987; 169; . DIP DIP-32871N; -; . IntAct P25705; 61; . MINT MINT-1163289; -; . STRING 9606.ENSP00000282050; -; . ChEMBL CHEMBL2062351; -; . DrugBank DB07384; 1-ACETYL-2-CARBOXYPIPERIDINE; . DrugBank DB07394; AUROVERTIN B; . DrugBank DB08399; PICEATANNOL; . DrugBank DB04216; Quercetin; . iPTMnet P25705; -; . PhosphoSitePlus P25705; -; . SwissPalm P25705; -; . BioMuta ATP5A1; -; . DMDM 114517; -; . OGP P25705; -; . REPRODUCTION-2DPAGE P25705; -; . UCD-2DPAGE P25705; -; . EPD P25705; -; . PaxDb P25705; -; . PeptideAtlas P25705; -; . PRIDE P25705; -; . TopDownProteomics P25705-1; -. [P25705-1]; . DNASU 498; -; . Ensembl ENST00000282050; ENSP00000282050; ENSG00000152234. [P25705-1]; . Ensembl ENST00000398752; ENSP00000381736; ENSG00000152234. [P25705-1]; . Ensembl ENST00000590665; ENSP00000467037; ENSG00000152234. [P25705-3]; . Ensembl ENST00000593152; ENSP00000465477; ENSG00000152234. [P25705-2]; . GeneID 498; -; . KEGG hsa:498; -; . UCSC uc010dnl.2; human. [P25705-1]; . CTD 498; -; . DisGeNET 498; -; . GeneCards ATP5A1; -; . HGNC HGNC:823; ATP5A1; . HPA CAB013067; -; . HPA HPA040622; -; . HPA HPA044202; -; . MalaCards ATP5A1; -; . MIM 164360; gene; . MIM 615228; phenotype; . MIM 616045; phenotype; . neXtProt NX_P25705; -; . OpenTargets ENSG00000152234; -; . Orphanet 254913; Isolated ATP synthase deficiency; . PharmGKB PA25115; -; . eggNOG KOG1353; Eukaryota; . eggNOG COG0056; LUCA; . GeneTree ENSGT00550000074846; -; . HOVERGEN HBG001536; -; . InParanoid P25705; -; . KO K02132; -; . OMA KRFNEAQ; -; . OrthoDB EOG091G0D1M; -; . PhylomeDB P25705; -; . TreeFam TF300321; -; . Reactome R-HSA-1268020; Mitochondrial protein import; . Reactome R-HSA-163210; Formation of ATP by chemiosmotic coupling; . ChiTaRS ATP5A1; human; . GenomeRNAi 498; -; . PMAP-CutDB P25705; -; . PRO PR:P25705; -; . Proteomes UP000005640; Chromosome 18; . Bgee ENSG00000152234; -; . CleanEx HS_ATP5A1; -; . ExpressionAtlas P25705; baseline and differential; . Genevisible P25705; HS; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0031012; C:extracellular matrix; IDA:BHF-UCL; . GO GO:0016020; C:membrane; IDA:UniProtKB; . GO GO:0005743; C:mitochondrial inner membrane; IDA:UniProtKB; . GO GO:0005759; C:mitochondrial matrix; TAS:Reactome; . GO GO:0005753; C:mitochondrial proton-transporting ATP synthase complex; IDA:UniProtKB; . GO GO:0005739; C:mitochondrion; IDA:UniProtKB; . GO GO:0043209; C:myelin sheath; IEA:Ensembl; . GO GO:0005886; C:plasma membrane; IDA:UniProtKB; . GO GO:0045261; C:proton-transporting ATP synthase complex; catalytic core F(1); IEA:UniProtKB-KW GO GO:0005524; F:ATP binding; ISS:UniProtKB; . GO GO:0042288; F:MHC class I protein binding; IDA:UniProtKB; . GO GO:0046933; F:proton-transporting ATP synthase activity; rotational mechanism; ISS:UniProtKB GO GO:0003723; F:RNA binding; IDA:UniProtKB; . GO GO:0022857; F:transmembrane transporter activity; IC:UniProtKB; . GO GO:0006754; P:ATP biosynthetic process; NAS:UniProtKB; . GO GO:0009790; P:embryo development; ISS:UniProtKB; . GO GO:0006629; P:lipid metabolic process; ISS:UniProtKB; . GO GO:0042776; P:mitochondrial ATP synthesis coupled proton transport; IC:UniProtKB; . GO GO:0001937; P:negative regulation of endothelial cell proliferation; IMP:UniProtKB; . CDD cd01132; F1_ATPase_alpha; 1; . Gene3D 2.40.30.20; -; 1; . Gene3D 3.40.50.300; -; 1; . HAMAP MF_01346; ATP_synth_alpha_bact; 1; . InterPro IPR023366; ATP_synth_asu-like; . InterPro IPR000793; ATP_synth_asu_C; . InterPro IPR033732; ATP_synth_F1_a; . InterPro IPR005294; ATP_synth_F1_asu; . InterPro IPR020003; ATPase_a/bsu_AS; . InterPro IPR004100; ATPase_F1/V1/A1_a/bsu_N; . InterPro IPR000194; ATPase_F1/V1/A1_a/bsu_nucl-bd; . InterPro IPR027417; P-loop_NTPase; . Pfam PF00006; ATP-synt_ab; 1; . Pfam PF00306; ATP-synt_ab_C; 1; . Pfam PF02874; ATP-synt_ab_N; 1; . PIRSF PIRSF039088; F_ATPase_subunit_alpha; 1; . SUPFAM SSF50615; SSF50615; 1; . SUPFAM SSF52540; SSF52540; 1; . TIGRFAMs TIGR00962; atpA; 1; . PROSITE PS00152; ATPASE_ALPHA_BETA; 1; .

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